RATIONALE: Studying samples of blood from patients with cancer and from healthy participants in the laboratory may help doctors learn more about changes that may occur in DNA. PURPOSE: This laboratory study is looking at blood samples from patients with prostate cancer and from healthy participants to identify a polymorphism that may help in the study of prostate cancer.
OBJECTIVES: Primary * Determine the incidence of the D104N COL18A1 polymorphism in patients with prostate cancer. Secondary * Determine the incidence of this polymorphism in African-American patients with prostate cancer. OUTLINE: This is a retrospective, multicenter study. DNA is extracted from preexisting serum samples and polymerase chain reaction is performed to determine the genotype pattern. PROJECTED ACCRUAL: A total of 500 patients and 250 healthy participants will be accrued for this study.
Study Type
OBSERVATIONAL
Enrollment
750
Frequency of D104N COL18A1 polymorphism in patients with prostate cancer and in healthy participants
Frequency of D104N COL18A1 polymorphism in African-American patients with prostate cancer and in healthy participants
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