Comparison of Straumann Bone Ceramic and Bio-Oss With Guided Tissue Regeneration for Alveolar Ridge Preservation

Inclusion Criteria: * Patient must have voluntarily signed the informed consent * Males and females, 18 years to 75 years of age * Patient needs single tooth extraction in mandibular or maxillary incisor or pre-molar region and would benefit from prosthetic reconstruction with a dental implant * Patients must be committed to the study and must sign informed consent * Patient in good general health as documented by self assessment Exclusion Criteria: Systemic exclusion criteria * Patient who has any known diseases (not including controlled diabetes mellitus), infections or recent surgical procedures within 30 days of study initiation * Female patient who are pregnant or lactating or of child bearing potential not using acceptable methods of birth control (hormonal, barriers or abstinence * Patient who are on chronic treatment (i.e., two weeks or more) with any medication known to affect oral status (e.g., phenytoin, dihydropyridine calcium antagonists, cyclosporine, and non-steroidal anti-inflammatory drugs) within one month of baseline visit * Patient who are on concomitant anticoagulant therapy of warfarin (coumadine), clopidogrel, ticlopidine or once daily asprin of more than 81 mg. * Patient who knowingly has HIV or Hepatitis * Physical handicaps that would interfere with the ability to perform adequate oral hygiene * Patient who has undergone administration of any investigational drug within 30 days of study initiation. * Alcoholism or chronically drug abuse causing systemic compromisation * Patient who is a heavy smoker (\>10/cigarettes per day). * Patient is suffering from a known psychological disorder * Patient has limited mental capacity or language skills such that study information cannot be understood, informed consent cannot be obtained, or simple instructions cannot be followed Local exclusion criteria * Uncontrolled or untreated periodontal disease * Bone defects that excludes implant restoration * Patient who has a full mouth plaque level \>30 % at the enrolment visit * Mucosal diseases such as erosive lichen planus * History of local radiation therapy * Presence of oral lesions (such as ulceration, malignancy) * Severe bruxing or clenching habits * Persistent intraoral infection * Patients presenting clinical and radiological signs and symptoms of maxillary sinus disease * Patient presents an acute endodontic lesion in the test tooth or in the neighbouring areas to the experimental procedure (sites with presence of an asymptomatic chronic lesion are eligible)