The purpose of this study is to evaluate the efficacy and safety of various doses of YM150 (the experimental drug) compared to enoxaparin in the prevention of venous thromboembolism in patients that are undergoing elective hip replacement surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
1,992
oral
SC injection
Incidence of symptomatic Venous Thromboembolisms and death from all causes
Time frame: 12 days
Incidence of all Venous Thromboembolic events
Time frame: Until day 12, during the treatment period, follow-up period and entire study period
Incidence of Bleeding events
Time frame: During the treatment period, follow-up period and entire study period
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Phoenix, Arizona, United States
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Phoenix, Arizona, United States
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Tuscon, Arizona, United States
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Little Rock, Arkansas, United States
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Long Beach, California, United States
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Torrance, California, United States
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Aurora, Colorado, United States
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DeLand, Florida, United States
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Pinellas Park, Florida, United States
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Sarasota, Florida, United States
...and 146 more locations