Impact of Myfortic on Gastrointestinal (GI) Prophylaxis in Maintenance Renal Transplant Patients

Inclusion Criteria: * Patients who have completed the parent study, US02. * Patients on GI medications. * Patients currently receiving Myfortic (all dosages are allowed), neoral or tacrolimus with or without corticosteroids as part of their immunosuppressive regimen for at least two weeks. * Patients with and/or without mild GI complaints (e.g. upper abdominal pain, dyspepsia, anorexia, nausea, vomiting) with or without diarrhea. * Females of childbearing potential must have a negative pregnancy test prior to the inclusion period. The test should be performed at Baseline visit. If positive, the patient will not be included. Effective contraception must be used during the trial, and for 4 weeks following discontinuation of the study medication. * Patients who are willing and able to participate in the full course of the study and from whom written informed consent has been obtained. Exclusion Criteria: * Evidence of graft rejection or treatment of acute rejection within 14 days prior to Baseline visit. * Patients who have received an investigational immunosuppressive drug within 4 weeks prior to study entry. * Females of childbearing potential who are planning to become pregnant, who are pregnant and/or lactating, who are unwilling to use effective means of contraception. * Patients with thrombocytopenia (\<75,000/mm3), with an absolute neutrophil count of \<1,500/mm3 and/or leukocytopenia (\<4,000/mm3), and/or hemoglobin \<9.0g/dL prior to enrollment. * Presence of clinically significant infection requiring continued therapy, severe diarrhea or active peptic ulcer disease that would interfere with the appropriate conduct of the study. * Evidence of severe liver disease (incl. abnormal liver profile i.e. AST, ALT or total bilirubin \>or= 3 times ULN). * Abnormal physical or laboratory findings of clinical significance within 2 weeks of inclusion which would interfere with the objectives of the study. * Evidence of drug and/or alcohol abuse. * Inability to self-administer the GSRS, GIQLI and PGWBI questionnaires. * Patients receiving \>10mg/day prednisone dose.