Climacterium is marked by hypoestrogenism and it is associated to drastic vasomotors symptoms, genital atrophy and humor alteration. Additionally, these symptoms impair sexual life and life quality. These effects can be counteracted by administration of estrogen therapy. However, estrogen therapy has side effects and isoflavone has been proposed as an estrogen substitute in reposition therapy. The aim of the randomized controlled trial is to evaluate the effects of isoflavone in the sex life assessed by a modified McCoy's sexual questionnaire.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
1 mg daily for 6 months
150 mg isoflavone daily for 6 months
sugar pill daily for six months
Ambulatório de Ginecologia Endócrina
São Paulo, São Paulo, Brazil
RECRUITINGMcCoy's sexual questionnaire
Time frame: at recruitment and six months later
Kupperman's index
Time frame: at recruitment and six months later
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