Predictors of Early Chest Infection in Acute Ischemic Stroke

University of Rostock530 enrolled

Overview

Pneumonia is a frequent complication of acute stroke and is associated with increased mortality and long-term impairment in the affected subjects. In previous studies, a number of clinical (e.g., dysphagia, severe neurological impairment, mechanical ventilation), radiological (e.g., large infarctions in the territory of middle cerebral artery, insular infarction) and biochemical (e.g., increased serum levels of C-reactive protein, decreased levels of CD4+ T-lymphocytes) findings have been reported as risk factors of stroke-related chest infection. The present study (PRECAST) aims to identify a small set out of these previously described risk factors that can predict stroke-related pneumonia with high sensitivity and specificity.

Study Type

OBSERVATIONAL

Enrollment

530

Conditions

Acute Ischemic Stroke Pneumonia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * acute ischemic stroke * admission to the neurological intensive care unit or stroke unit within 24 hours after stroke onset * clearly assessed brain lesion location Exclusion Criteria: * previous large (non-lacunar) stroke * chest infection present already on hospital admission * mechanical ventilation already on day 1 or 2 after hospital admission * treatment with immunosuppressive drugs

Predictors of Early Chest Infection in Acute Ischemic Stroke

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes