Benefit of Roux-en-Y (R-Y) Reconstruction After Pancreaticoduodenectomy

Kochi University40 enrolled

Overview

One of the most common complications of pancreaticoduodenectomy (PD) is delayed gastric emptying (DGE), otherwise known as "gastroparesis," which is not fatal but results in prolonged hospital stay and increased hospital costs. Delayed gastric emptying is defined as nasogastric decompression after postoperative day (POD) 10 or a failure to tolerate a regular diet after POD 14. The incidence of DGE has been reported to range from 5% to 72%.

We hypothesized that the hand-sewn, two-layered, or continuous suture, could induce anastomotic edema to indeed the afferent peristalsis, which is one of the causes of DGE.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Pancreatic Cancer

Interventions

R-Y reconstructionPROCEDURE

The reconstruction was performed by R-Y anastomosis.

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * These patients were to undergo elective pancreatic head resection for the treatment of periampullary mass Exclusion Criteria: * A body weight loss greater than 10% during the six months prior to surgery * The presence of distant metastases * Seriously impaired function of vital organs due to respiratory, renal or heart disease

Locations (1)

Kochi Medical School

Nankoku, Kochi, Japan

RECRUITING

Outcomes

Primary Outcomes

the incidence of DGE

Time frame: 3-6 months

Secondary Outcomes

the incidence of other complication associated with reconstruction

Time frame: 3-6 months

Central Contacts

Takehiro Okabayashi, MD, PhD

CONTACT

81-88-880-2370 tokabaya@kochi-u.ac.jp

Kazuhiro Hanazaki, Prof

CONTACT

81-88-880-2370 im31@kochi-u.ac.jp

Data from ClinicalTrials.gov

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