Ginkgo Biloba for the Treatment of Vitiligo Vulgaris in Adolescents

Inclusion Criteria: * • males and females * 12 to 18 years old * self selected candidates identifying themselves to suffer with vitiligo vulgaris of any duration * minimum VASI score of 4, no maximum score (corresponding to a 3cm2 completely (100%) depigmented lesion, or a 6cm2 50% depigmented lesion) * stable or progressing vitiligo * mentally competent subjects able to adhere to the given protocol and treatments administered as interventions * normal on physical examination at the pre-study intake, and in the case of abnormalities the health care practitioner considers them to be clinically insignificant * written and informed consent * the potential candidate must have a family doctor that they have seen in the last 12 months * negative pregnancy test for menstruating women and if sexually active, a willingness to practice adequate birth control for the duration of the trial * diagnosis of vitiligo confirmed by supervising medical doctor Exclusion Criteria: * • use of medications contraindicated with Ginkgo biloba: * daily use of acetylsalicylic acid, ibuprofen, NSAIDs, fish oils, vitamin E * any prescription or use of blood thinners, anticoagulants, anti-platelet drugs, pentoxifylline, clotting factor replacements, antihypertensive medications, Thiazide diuretics, Acetylcholinesterase inhibitors, anticonvulsants, hypoglycemic agents, MAOI, SSRI, Nifedipine, Papaverine, Yohimgine, Sildenafil * history of diabetes, seizures, haemophilia * allergy or sensitivity to Ginkgo biloba or other constituents in the capsule * any treatment for vitiligo within the last 2 months * current use of Ginkgo biloba or within the last 2 months * mentally or physically incapacitated such that assent or informed consent cannot be obtained. * any history or other condition which the study physician regards as clinically significant to the study * a major illness considered to be clinically significant by the study physician within 2 months of the study start date * current participation in another intervention trial. * pregnancy or intent to become pregnant in the next 4 months * current alcoholism or substance abuse. * current history of tumors, any history of skin cancer * any current serious disorders determined to be clinically significant to the study. * breast feeding women * no prior skin grafts or surgeries, or scheduled surgeries of any kind. * any abnormalities on the INR, PTT, or CBC tests at baseline