A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults

Inclusion Criteria: * Healthy male and/or female subjects between the ages of 18 and 55 years, inclusive. * Subjects who display the CYP2D6 extensive, intermediate, ultra-rapid, or poor metabolizer statuses. Exclusion Criteria: * A known history of hypersensitivity or previous intolerance to Dimebon or other antihistamines. * Subjects with any previous history of seizures, convulsions, epilepsy, or significant head injury. * Evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic, or allergic disease (including drug allergies, but excluding untreated, asymptomatic, seasonal allergies at time of dosing).