Trial of Endocrine Against Locoregional Therapy First in Postmenopausal Women With Early Breast Cancer

Inclusion Criteria: * Informed consent * Age 60 years or older * Measurable non-metastatic and non-inflammatory breast cancer * Tumor of 2 cm or larger * ER and/or PgR positive tumor * Co-morbidity index 0 - 3, e.g., no other serious medical condition Exclusion Criteria: * Prior medical therapy for a malignant disease, including aromatase inhibitors * Distant metastasis * Need for chemotherapy * Past or current history of other neoplasms (except for curative treated basal skin cancer or in situ carcinoma of the cervix uteri) * Treatment with a non-approved drug within 30 days