The Use of Narrow Band Imaging in Screening Colonoscopy

Valduce Hospital206 enrolled

Overview

Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa. Conflicting data exist on the ability of NBI in to improve detection of colonic neoplasm; the impact of NBI is being tested in several screening scenarios. The investigators evaluated whether the routine use of NBI, compared to white light (WL), during the withdrawal phase of screening colonoscopy improved adenoma detection.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

206

Conditions

Colonoscopy

Interventions

Narrow Band ImagingPROCEDURE

Narrow Band Imaging

Eligibility

Sex: ALLMin age: 50 YearsMax age: 69 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 50-69 year-old asymptomatic subjects at average-risk of CRC * positive FOBT participating in a national mass-screening program and referred for colonoscopy Exclusion Criteria: * ongoing anticoagulation therapy * inadequate bowel cleansing * incomplete colonoscopy * refusing to participate

Outcomes

Primary Outcomes

Adenoma Detection

Detection of adenoma, defined as the number of patients with \> 1 adenoma, under White Light or NBI visualization

Time frame: duration of colonoscopy procedure

Secondary Outcomes

Detection of Flat and/or Depressed Adenomas

number of patients with at least 1 flat and/or depressed adenoma

Time frame: duration of colonoscopy procedure

Data from ClinicalTrials.gov

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