This study is a comparison of two most commonly used modes of weaning and the outcomes in the two groups.
Patients ventilated for more than 24 hours are randomized into two groups - one group of patients undergo gradual reduction of pressure support and in the other, T tube trials are used for weaning. The outcomes are compared in the two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
TRIPLE
Enrollment
130
These patients are weaned by gradual reduction of pressure support and extubated when they tolerate a pressure support of 7 cm of water for one hour.
These patients are weaned by giving a T piece trial with 8 cm of water pressure support and extubated when they tolerate it for one hour.
Postgraduate Institute of Medical Education and Research
Chandigarh, Chandigarh, India
RECRUITINGRate of weaning failure
Time frame: 48 hours from extubation
Occurence of ventilator associated pneumonia
Time frame: Until the date of discharge from hospital
Reintubation rates
Time frame: 48 hours
Mortality rates
Time frame: Until the time of discharge from hospital
Duration from start of weaning to extubation
Time frame: In hospital stay
Role of various factors that may influence the weaning outcome and hence predict the probability of successful weaning in a patient
Time frame: during ICU stay
The influence of weaning outcome on mortality and the other complications of mechanical ventilation
Time frame: during hospital stay
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