There is evidence that controlling total amount of carbohydrates is a strategy for controlling glucose levels in diabetes mellitus. There is not major evidence that any given macronutrient percentage may be recommended to treat a woman with Gestational Diabetes Mellitus (GDM). In the investigators' country, insulin is the second-line treatment once medical nutrition therapy (MNT) has failed to control glucose levels during pregnancy. Insulin treatment is more expensive and not as well accepted as MNT. The investigators have designed a randomized-controlled trial to assess whether a diet with 40% total calories from carbohydrates may reduce the need of insulin treatment in women with gestational diabetes, without having unfavourable pregnancy outcomes, in comparison with a diet with 55% total calories from carbohydrates.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
152
Diet with 40% total calories from carbohydrates. In the "Low-CHO" arm, 15% of calories from carbohydrates will be substituted by monounsaturated fat.
Diet with 55% total calories from carbohydrates.
Hospital Universitari Arnau de Vilanova
Lleida, Lleida, Spain
Need of insulin treatment for GDM
Time frame: Day of delivery
Time from GDM diagnosis free of insulin treatment
Time frame: Day of delivery
Maternal ketonemia and/or ketonuria
Time frame: Day of delivery
Maternal morbidity
Time frame: Day of delivery
Fetal morbidity
Time frame: 1 month after delivery
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