The broad aim is to determine efficacy of a weight loss diet higher in protein and lower in carbohydrate combined with low intensity exercise to favorably impact body composition, bone health, physical function, metabolic disease and quality of life compared to a conventional higher carbohydrate diet in overweight women over age 60.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
31
Loss of 10% baseline weight over 6 months, with whey protein isolate supplemented at 50g/day (two 25 g doses taken at breakfast and afternoon snack mixed with food or beverage)
Loss of 10% baseline weight over 6 months, with whey protein isolate supplemented at 50 g / day (two 25 g doses at breakfast and afternoon snack mixed with food or beverage)
University of Illinois at Urbana-Champaign
Urbana, Illinois, United States
Bone and body composition: Weight, percent fat, muscle and fat distribution in the thigh and abdomen and bone density and structural quality assessed by DXA and structural MRI
Time frame: Baseline and post 6 months weight loss
Physical function: balance, gait, strength and activities of daily living
Time frame: Baseline and post 6 months weight loss
Quality of life
Time frame: Baseline and post 6 months weight loss
Metabolic syndrome: insulin resistance, blood pressure, blood lipids, waist circumference
Time frame: Baseline and post 6 months weight loss
Acid-base balance
Time frame: Baseline and post 1 and 6 months weight loss
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