Recently, Nanto et al. reported that cilostazol effectively prevented restenosis in a retrospective analysis of 121 femoropopliteal artery lesions in percutaneous transluminal angioplasty (PTA) patients who had undergone PTA. In a prospective 3-year follow-up study in 127 patients with similar diseases, the patency rate was significantly higher in the cilostazol group than in the ticlopidine group. It was also found that cilostazol markedly inhibited restenosis during the first 1-year period following endovascular therapy when restenosis is most frequently observed. In addition, there have been sporadic reports that cilostazol was effective in preventing post-stenting restenosis in the coronary artery area. Based on these results, this multicenter study is going to be conducted to prospectively evaluate the usefulness of cilostazol in lower limb endovascular therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
200
200 mg/day BID
Shinkoga Hospital
Kurume, Fukuoka, Japan
NOT_YET_RECRUITINGHyogo College of Medicine Hopital
Nishinomiya, Hyōgo, Japan
NOT_YET_RECRUITINGDepartment of Cardiology, Kanazawa Cardiovascular Hospital
Kanazawa, Ishikawa-ken, Japan
NOT_YET_RECRUITINGDepartment of Cardiology,Naganoken Koseiren Shinonoi
Nagano, Nagano, Japan
RECRUITINGOmihachiman Community Medical Center
Ōmihachiman, Shiga, Japan
NOT_YET_RECRUITINGKansai Rosai Hospital and seven others
Amagasaki, Japan
RECRUITINGKishiwada Tokushukai Hospital
Kishiwada, Japan
RECRUITINGKokura Memorial Hospital
Kitakyusy, Japan
RECRUITINGShinshu University Hospital
Matsumoto, Japan
RECRUITINGCaress Sapporo Tokeidai Memorial Hospital
Sapporo, Japan
RECRUITING...and 3 more locations
Angiographic restenosis rate
Time frame: 12 months +- 1 month
Cardiovascular events
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