Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG)

Inclusion Criteria: * Diagnosis of primary open-angle glaucoma * Male or female at least 18 years of age and able to provide written informed consent * Mean IOP (at baseline visit after washout of any medications) must be 22 mm Hg and no greater than 38 mm Hg * Likely to be available and willing to attend follow-up visits Exclusion Criteria: * Angle closure glaucoma * Secondary glaucomas * Prior glaucoma procedures * Elevated episcleral venous pressure from history of active thyroid orbitopathy, carotid-cavernous fistula, orbital tumors, or orbital congestive disease