The aims of this prospective, randomized study are: * To assess the effect of clean intermittent catheterization (CIC) * To investigate if MS patients will have symptom reduction (urgency, frequency, nocturia and incontinence) when using CIC in combination with anticholinergic drugs * To identify at what volume of Postvoid Residual (PVR) urine, starting CIC improves bladder control and QoL * To increase the evidence of CIC, and support clinical guidelines of bladder management in MS patients
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Anticholinergic medication according to clinical practice and investigator´s judgement, either started at screening visit or continued from before study start, and start of CIC using LoFric Primo catheters, i.e. Drug + Device.
Anticholinergic medication according to clinical practice and investigator´s judgement, either started at screening visit or continued from before study start, i.e. Drug.
Centre Hospitalier Universitaire de Liège Ourthe Ambléve
Esneux, Belgium
UZ Gasthuisberg
Leuven, Belgium
St. Hedwig Hospital, Department of Urology
Berlin, Germany
UMC ST Radboud Nijmegen, Department of Urology
Nijmegen, Netherlands
University College of London, Institute of Neurology
London, United Kingdom
Percent Change From Baseline in Frequency of Micturition Per Day at 8 Weeks.
Number of micturitions per day was assessed using a patient diary during three days at baseline and after 8 weeks of treatment. The relative change in mean number of micturitions was compared between the groups. The change was calculated as percent change = ((measure at 8 weeks - measure at baseline)/measure at baseline)\*100%.
Time frame: Baseline and 8 weeks after randomization.
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