The purpose of this study is to determine whether or not vitamin D supplementation can improve physical performance in persons with severe chronic obstructive pulmonary disease (COPD).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
39
2000 I.U. daily for 6 weeks
Placebo (sugar pill) daily for 6 weeks
Minneapolis VA Medical Center
Minneapolis, Minnesota, United States
Change in Short Physical Performance Battery (SPPB) Score
SPPB measures lower extremity strength using 3 simple office-based tests to assess standing balance, gait speed, and chair stands. The composite SPPB score ranges from 0 (worst performance) to 12 (best performance). The minimal clinically important difference is not fully agreed upon, although a difference of 1.0 point has been used in many studies.
Time frame: Baseline and 6 weeks
Change in Blood Level of Vitamin D (25-hydroxyvitamin D)
Time frame: Baseline and 6 weeks
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