Safety and Immunogenicity Study of Intramuscular CCS/C-adjuvanted Influenza Vaccine in Elderly

Inclusion Criteria: * 65 years of age or older, mentally competent, willing and able to give written informed consent prior to study entry, male or female; * able to comply with all the study requirements; * in stable good health as determined by medical history; physical examination; clinical judgment of the investigator. * Have adequate renal function (renal clearance of at \> 30ml/min) * Have normal liver function (hepatic transaminases \[ALT and AST\] \< 43 U/L) * Have hemoglobin \> 11.5 g/L Exclusion Criteria: * Any serious chronic or acute disease (in the judgment of the investigator) including but not limited to: cancer, except for localized skin cancer; * Advanced congestive heart failure; Acute exacerbation of Chronic obstructive pulmonary disease (COPD); Autoimmune disease, Acute or progressive hepatic disease; Acute or progressive renal disease with a renal clearance of at \< 30ml/min ; Severe neurological or psychiatric disorder; History of Guillain Barré syndrome; Severe asthma. * Clinically significant symptoms of neurological disease; untreated hypertension; increased liver enzymes. * History of any anaphylactic reaction and/or serious allergic reaction following a vaccination