Prokinetic Drugs and Enteral Nutrition

Universitair Ziekenhuis Brussel60 enrolled

Overview

The purpose of this study is to compare the effect of two drugs that can help in the prevention of regurgitation during the administration of enteral nutrition and define which one is the most effective.

Two prokinetic drugs (metoclopramide and erythromycin) will be compared during the administration of enteral nutrition in critically ill patients. We would like to know which one is the most effective in preventing regurgitation and risk of aspiration, which is a common complication of enteral nutritional support. This will be evaluated by measuring gastric residue every six hours.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Critically Ill Enteral Nutrition

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * critically ill patients * intubated * mechanically ventilated * 18 or older age * enterally fed Exclusion Criteria: * prokinetic drugs before start study * allergy to study medication * interactions odf study medication with other drugs * recent gastro-intestinal surgery * history of esophagectomy or gastrectomy * suspicion of gastrointestinal perforation * myasthenia gravis * liver dysfunction * less than 7 days in study * gastro- or jejunostomy

Locations (1)

UZBrussels

Jette, Belgium

Central Contacts

Nele Van De Winkel

CONTACT

00324773348 nelevandewinkel@hotmail.com

Data from ClinicalTrials.gov

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