Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery

Inclusion Criteria: * Subjects is scheduled for elective primary total knee replacement surgery * Written informed consent obtained before screening Exclusion Criteria: * Subject has history of deep vein thrombosis and/or pulmonary embolism * Subject has a hemorrhagic disorder and/or coagulation disorder * Subject has had clinically important bleeding occurred within 90 days prior to the screening visit * Subject has an acute bacterial endocarditis, retinopathy, hypertension, or thrombocytopenia * Subject is receiving anticoagulants/antiplatelets