Connecting the Lab to Everyday Life: The Relevance of Executive Dysfunction to Participation and Quality of Life in Parkinson's Disease (PD) Without Dementia

Washington University School of Medicine174 enrolled

Overview

The overall purpose of this research is to learn how Parkinson's disease affects thinking and memory in everyday life. Participation will involve thinking tests, questionnaires and interviews about thinking and activities in everyday life.

Study Type

OBSERVATIONAL

Enrollment

174

Conditions

Parkinson's Disease

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria PD participants: * WUSM Movement Disorders Clinic patients * males or females between 40 and 70 * meet criteria for idiopathic typical PD * classified at Hoehn \& Yahr12 stage I, II, or III * are currently treated with levodopa/carbidopa Inclusion Criteria Control: * The groups will be matched for age, education and gender * No Parkinson Disease Exclusion Criteria PD participants and Control: * suspected dementia * treatment with certain dopaminergic, anticholinergic or benzodiazepine medications * other neurological problems * brain surgery * history or current psychotic disorder * any condition which would interfere with testing * control only: a biological family history of PD and being a caregiver or spouse of someone who has PD

Locations (1)

Washington University School of Medicine

St Louis, Missouri, United States

Data from ClinicalTrials.gov

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