Pilot Study of Hippocampal Function in Type 1 Diabetes Mellitus (T1DM)

Washington University School of Medicine91 enrolled

Overview

This study is an expansion of a previous study done to determine how thinking skills relate to hypoglycemia (low blood sugar) and certain regions of the brain in children and adolescents. In this study, the investigators are testing thinking skills and measuring brain activity in adolescents with and without type 1 diabetes mellitus.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Type 1 Diabetes Mellitus

Eligibility

Sex: ALLMin age: 13 YearsMax age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 13 - 18 * Right handed * Diagnosis of Type 1 Diabetes OR normal sibling control * If diabetic, then diagnosis for at least 2 years Exclusion Criteria: * Pregnant or lactating * Chronic disease other than well-controlled asthma, or Hashimoto's thyroiditis. * Other current serious medical illness * Co-morbid psychiatric illness * Co-morbid neurological illness * Pre-maturity at birth * Contraindication to MRI scan * orthodontic braces.

Locations (1)

Washington University School of Medicine

St Louis, Missouri, United States

Data from ClinicalTrials.gov

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