Exemestane (Aromasine) + Tamoxifen - Breast Neo-Adjuvant

Inclusion Criteria: * Breast cancer histologically proven by a 14 G or 16 G micro-biopsy to have confirmation of the diagnosis, evaluation histology prognosis grade, hormone receptors and to obtain a sample for the study of biological factors. * Menopausal patients as defined as follows: * Natural menopause \>= 1 year, or * Surgical ovariectomy. * T unilateral tumor\> 3 cm, N 1-2, M0 or M +, non-inflammatory. * Hormone receptor positive. RE positive or PR positive with histochemical technique (+ 10% of cells express the receptor) * No previous treatment of the disease by chemotherapy, hormone therapy, surgery or radiotherapy. Discontinuation of replacement therapy of menopause for at least 1 month * Age\>= 60 years * Evaluable disease * Performance Status \<= 2 * Biological function using the following criteria: * neutrophils \>= 2.10E9 / l, * Platelets\> = 100.10E9 / l, * Hemoglobin\> = 10 g / dl, * Creatinine \<= 1.5 x upper normal, * Total bilirubin \<= 1.25 x the upper normal * Transaminases (AST and ALT) \<= 1.5 x upper normal, * Alkaline phosphatase \<= 2.5 x upper normal. * Cardiac Function: electrocardiogram (ECG) normal. * Signed written consent before any procedure related to the study. Exclusion Criteria: * Men * Non Menopausal Patients * Patients with hormone receptor negative: PR- and RE - * Contra-indication to anti-estrogens (risk thrombi arteria) * Tumor \<3 cm operable * Tumor inflammatory T4d (PEV 2 or 3). * Extensive hepatic lesions (\> 1 / 3 of liver volume) * Uncontrolled cardiac disease such as angina, congestive heart failure, or arrhythmia requiring medical treatment or history of myocardial infarction within 3 months before. * History of cancer except skin cancer and basal cell cancer in situ of the cervix (a contralateral breast cancer had been no systemic treatment will be admitted). * Chronic diseases (somatic or psychiatric) in poor prognosis. * Patients who for reasons of family, social, geographical or psychological can not be followed properly. * Patients under law protection