Abstract Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in Canada. COPD is not just a disease of men, nor is it solely a disease in old age. Women have been underrepresented and early disease has not been studied. Underdiagnosis of COPD remains a significant problem, and it may indicate an unmet healthcare need. This can potentially results not only in a patient been misinformed, but can lead to incorrect management. Epidemiological research is needed to develop a framework to combat this major health problem, by better characterization of the population of men and women at risk and patients with early disease, by better understanding which factors modifiable through health interventions are related to health perception (health-related quality of life) and disease evolution. This will be possible through a nationwide study, the Canadian Cohort Obstructive Lung disease (CanCOLD), a prospective longitudinal study. The CanCOLD study is built on the current ongoing prevalence nationwide study, the Canadian Obstructive Lung disease "COLD" study. The CanCOLD will be the first study to assess prevalence of disease across Canada and its consequence in men and women, and to evaluate a conceptual model of disease severity based on patient's health perception (health-related quality of life). Ultimately, this project will extend to a longitudinal follow up (3 years or beyond) and will allow to have a better understanding of the lifestyle risk factors, not only smoking but also diet, physical activity, and co morbid conditions. This will be a great asset to shift from management of a single risk factor (tobacco control) to total COPD risk management. The results of the study will greatly help to assist decision makers in developing policies to improve the diagnosis, the management of COPD and to optimize health care services use.
Study Type
OBSERVATIONAL
Enrollment
1,500
Health Sciences Centre
Calgary, Alberta, Canada
St-Paul's Hospital
Vancouver, British Columbia, Canada
Halifax Infirmary
Halifax, Nova Scotia, Canada
Kingston General Hospital
Kingston, Ontario, Canada
Ottawa Hospital General
Ottawa, Ontario, Canada
University of Toronto
Toronto, Ontario, Canada
Montreal Chest Institute
Montreal, Quebec, Canada
Royal University Hospital
Saskatoon, Saskatchewan, Canada
Institut universitaire de cardiologie et de pneumologie de Québec
Québec, Canada
What risk factors other than smoking determine the development and progression of COPD.
Time frame: One visit a year every 18 months
What are the combinations of the disease and patient attributes that differentiate individuals (men/women) with COPD as they relate to relevant outcomes (symptoms, exacerbations, disease progression or death)
Time frame: One visit a year 18 months
Is early detection of COPD with spirometry meaningful according to sex and ageing.
Time frame: One visit a year 18 months
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