The aim of the present study was to evaluate the additional effect of sudden visceral fat reduction by omentectomy on Metabolic Syndrome, acute phase reactants and inflammatory mediators in patients with morbid obesity undergoing Laparoscopic Roux-en-Y Gastric Bypass.
Although weight loss controls Metabolic Syndrome and reduces the level of inflammatory markers in patients with Morbid Obesity, patients may enjoy the benefit achieving metabolic control before significant weight loss occurs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Laparoscopic Roux-en-Y Gastric Bypass was performed according to the following standards: Gastric pouch was constructed using the lesser curvature of the stomach. A 45mm stapler was initially fired horizontally 2 to 3 cm below the gastroesophageal junction and then 2 o 3 additional fires towards the angle of His and against a 32 French intragastric tube completed the vertical transection. Lengths of the biliopancreatic and alimentary limbs were approximately 50, and 150 cm respectively. An antecolic and antegastric gastrojejunostomy, 1.0 to 1.5 cm in size was hand sewn and the jejuno-jejunostomy was completed in a latero-lateral fashion using one fire of 45 mm lineal stapler with hand sewn closure of the common enterotomy.
After laparoscopic gastric bypass, the greater omentum was divided in the middle from the free edge to the colonic margin using ultrasonic energy. Attachments between the omentum and the transverse colon were dissected. The omentum was detached from the stomach transecting the vessels between the right gastroepiploic vessels and the greater curvature of the stomach. Once the omentum was freed from the stomach, the duodenum and the lower pole of the spleen, it was extracted from the abdominal cavity in a sterile plastic bag.
Components of Metabolic Syndrome (Body Mass Index)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Body Mass Index)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (Body Mass Index)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Body Mass Index)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Body Mass Index)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (Systolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Systolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (Systolic Blood Pressure)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Systolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Systolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (Diastolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Diastolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (Diastolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Diastolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Diastolic Blood Pressure)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (Glucose)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Glucose)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (Glucose)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Glucose)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Glucose)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (Insulin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Insulin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Insulin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Insulin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (Total Cholesterol)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Total Cholesterol)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (Total Cholesterol)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Total Cholesterol)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Total Cholesterol)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (Triglycerides)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Triglycerides)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (Triglycerides)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Triglycerides)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Triglycerides)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (Low-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (Low-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (Low-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (Low-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (Low-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Components of Metabolic Syndrome (High-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Components of Metabolic Syndrome (High-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 month
Components of Metabolic Syndrome (High-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Components of Metabolic Syndrome (High-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Components of Metabolic Syndrome (High-Density Lipoproteins)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement
Time frame: Basal
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Acute Phase Reactants and Inflammatory Mediators (Interleukine-6)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement
Time frame: Basal
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Acute Phase Reactants and Inflammatory Mediators (C-reactive Protein)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement
Time frame: 1 year
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement
Time frame: 6 months
Acute Phase Reactants and Inflammatory Mediators (Tumor Necrosis Factor-alpha)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Acute Phase Reactants and Inflammatory Mediators (Leptin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Acute Phase Reactants and Inflammatory Mediators (Leptin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Acute Phase Reactants and Inflammatory Mediators (Leptin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Acute Phase Reactants and Inflammatory Mediators (Leptin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: Basal
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 3 months
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 6 months
Acute Phase Reactants and Inflammatory Mediators (Adiponectin)
Absolute values are presented, a basal value is provided in a previous outcome measure to determine the improvement.
Time frame: 1 year