Brain-derived Neurotrophic Factor Participates in Visceral Hyperalgesia in Irritable Bowel Syndrome (IBS) Patients

Shandong University30 enrolled

Overview

Brain-derived neurotrophic factor (BDNF), originally known to be a member of the nerve growth factor family, has aroused attention as a modulator in visceral hyperalgesia recently. Visceral hypersensitivity is recognized as a clinical hallmark in IBS patients. So in this study, the investigators will focus on the role of BDNF in colonic hyperalgesia in IBS patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Irritable Bowel Syndrome

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients diagnosed with irritable bowel syndrome. Exclusion Criteria: * Patients have similar clinical symptoms as IBS, yet there is morphologic changes in the intestine.

Data from ClinicalTrials.gov

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