Effects of Oxybutynin Topical Gel on Gastric Emptying

Phase 1CompletedNCT00926926

Watson Pharmaceuticals23 enrolled

Overview

This study explores the effect of oxybutynin topical gel on gastric emptying

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

QUADRUPLE

Enrollment

Conditions

Healthy

Interventions

Oxybutynin Chloride GelDRUG

Once daily for 7 days, followed by single dose of acetaminophen

Placebo GelDRUG

Once daily for 7 days, followed by single dose of acetaminophen

Eligibility

Sex: FEMALEMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adult, healthy, post-menopausal females Exclusion Criteria: * Patients for whom OTG or acetaminophen is contraindicated. * Abnormality of the GI tract. * Taking drugs that affect gastric motility.

Locations (1)

Unnamed facility

Saint Charles, Missouri, United States

Outcomes

Primary Outcomes

The effect of oxybutynin chloride topical gel administration on gastric emptying will be assessed by comparing the single dose relative bioavailability of acetaminophen

Time frame: After 7 days of treatment

Data from ClinicalTrials.gov

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