Clinical Evaluation of AutoFlow Mode During Mechanical Ventilation

Centre Hospitalier Victor Dupouy42 enrolled

Overview

The purpose of this study is to evaluate the long term use of AutoFlow mode during mechanical ventilation in ICU patients

Many new mechanical ventilation modes are proposed without clinical evaluation. Among them, "dual-controlled" modes, as AutoFlow, are supposed to improve patient-ventilator interfacing, and could led to lesser alarm. This study is a long term clinical evaluation of AutoFlow during assist-controlled ventilation, focusing on its efficacy (on gas exchange and outcome) and on ventilator alarms.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Ventilation, Mechanical

Interventions

AutoFlow mode on Evita 4 Dräger ventilatorsDEVICE

Activation of AutoFlow mode during assist-controlled ventilation

Evita 4 Dräger ventilatorsDEVICE

Assist-controlled ventilation without activation of AutoFlow mode

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * adult patients under assist-controlled ventilation with an Evita 4 ventilator (Dräger, France) for an expected duration of more than two days Exclusion Criteria: * coma * ventilation longer than 12 hours prior to inclusion * pregnancy * inclusion in another study

Locations (1)

Centre Hospitalier Victor Dupouy

Argenteuil, France

Outcomes

Primary Outcomes

gas exchange

Time frame: daily during mechanical ventilation

sedation length

Time frame: ICU discharge

ventilator alarm rates

Time frame: daily during mechanical ventilation

Secondary Outcomes

length of mechanical ventilation

Time frame: ICU discharge

ventilator asssociated pneumonia rate

Time frame: ICU discharge

SOFA score

Time frame: daily during mechanical ventilation

death rate

Time frame: ICU discharge

cumulative sedation drugs dosage

Time frame: ICU discharge

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.