The purpose of this study is to investigate the time course of PF-04764793 concentration in the blood following dosing by oral inhalation from dry powder inhalers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
36
Inhaled, 300/150, single dose
Inhaled, 300/150, single dose
Inhaled, 300/150, single dose + oral activated charcoal block
Pfizer Investigational Site
Singapore, Singapore
Plasma pharmacokinetic parameters: AUClast and Cmax
Time frame: 48 hours
Plasma pharmacokinetic parameters: AUC0-12, AUC0-24, AUCinf, Tmax and terminal half-life.
Time frame: 48 hours
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Inhaled, 300/150, single dose + oral activated charcoal block