The aims of this study are to examine the effect of repeated doses of AZD2066 and of caffeine, bupropion, tolbutamide, omeprazole, metoprolol and midazolam on the blood concentrations of each other
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
15
12 doses, Given as capsule, 2 mg \& 8 mg
2 doses, Given as Tablet, 2x50 mg
2 doses, Given as Tablet, half of 500 mg
Research Site
London, United Kingdom
Research Site
Manchester, United Kingdom
PK variables
Time frame: Frequent sampling occasions during
Safety variables (adverse events, blood pressure, pulse, safety lab)
Time frame: Frequent sampling occasions during
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
2 doses, Given as Tablet, 20 mg
2 doses, Given as Tablet, 7.5 mg