Safety Study of Colonoscopy Under Sedation

Inclusion Criteria: 1. Patient referred for colonoscopy with general anesthesia 2. Age above 18 et below 75 year 3. Patient who gave an informed consent Exclusion Criteria: 1. Age below 18 ou above 75 2. Need for gastroscopy in the same procedure than colonoscopy 3. History of surgery wih resection more extended than half of the colon 4. Dementia with autonomy loss or psychiatric disorder non controlled by therapeutic 5. Severe congestive heart failure or evolutive heart ischemia 6. Recent cerebral stroke 7. Hemodynamic instability 8. Respiratory failure, severe chronic obstructive pulmonary (including asthma) or progressive pneumothorax 9. Hepatic failure (Child-Pugh score\> 9) 10. Terminal renal failure 11 Hematopoietic disorders 12\. Pathology with expected survival shorter than the duration of the study and cancer excepted basal cell carcinoma of the skin 13. Alcohol consumption higher than 100 gr per day 14. Pregnancy or breastfeeding at the inclusion period