The presence of scar within heart muscle can act as a substrate for abnormal rhythm problems and lead to the developement of heart failure Clinical significance Correlation with biomarkers and genetic markers
Patients will undergo cardiovascular magnetic resonance (CMR) to include measurement of left ventricular volumes, ejection fraction, detection of inflammation (via STIR sequences) where appropriate, early gadolinium enhancement, late gadolinium enhancement, first pass perfusion using pharmacological stress imaging (contraindications to include comorbidities that do not permit pharmacological stress agents e.g. severe asthma, severe or symptomatic aortic stenosis)
Study Type
OBSERVATIONAL
Enrollment
3,000
Royal Brompton Hospital
London, United Kingdom
RECRUITINGAll cause mortality
Time frame: 3 years
Ventricular arrhythmias
Time frame: 3 years
Unplanned heart failure admissions
Time frame: 3 years
Ejection fraction
Time frame: 3
NYHA status
Time frame: 3
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