Endothelial Cell Loss After Cataract Surgery

Phase 3TerminatedNCT00932191

University of California, San Francisco39 enrolled

Overview

The purpose of this study is to compare two cataract surgical technique variations for removing the nucleus of the lens (central part of the lens) in terms of damage to the inner layer of the cornea which is called the endothelium. One variation uses more ultrasound energy and the other more mechanical force to break up the nucleus.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Cataracts

Interventions

Standard phacoemulsificationPROCEDURE

Cataract nucleus removal using standard amounts of ultrasound energy

Reduced ultrasound phacoemulsificationPROCEDURE

Cataract nucleus removal using less ultrasound energy and more mechanical energy.

Eligibility

Sex: ALLMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Visually significant moderate density cataract Exclusion Criteria: * Corneal or retinal pathology limiting visual potential to worse than 20/40 * Lens pathology including pseudoexfoliation or lens dislocation * Prior intraocular surgery * Age less than 40

Locations (1)

University of California San Francisco

San Francisco, California, United States

Outcomes

Primary Outcomes

Corneal endothelial cell loss by specular microscopy after cataract surgery

Time frame: 3 months post-operatively

Data from ClinicalTrials.gov

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