Cortisol Activity in Patients With Prader-Willi Syndrome and Healthy Controls

Children's Mercy Hospital Kansas City36 enrolled

Overview

The purpose of the study is to find out if people with Prader-Willi syndrome have a difference in the protein which changes inactive cortisone to the active stress hormone cortisol.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Prader-Willi Syndrome

Eligibility

Sex: ALLMin age: 6 MonthsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Prader-Willi syndrome confirmed by molecular testing, ages 6 months to adult * Controls: Age-matched, sex-matched, developmentally normal, BMI-controlled healthy or obese subjects Exclusion Criteria: * PWS subjects without molecular confirmation of the diagnosis * Subjects receiving glucocorticoid treatment within 3 months of evaluation * Subjects receiving growth hormone within one year prior to analysis

Data from ClinicalTrials.gov

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