Obesity has been found to be a risk factor for female infertility. Studies have indicated that obese men often have poor semen quality and require increased time to make partner pregnant. To date, no studies have investigated the effect of weight reduction on male fertility. The purpose of this study is to investigate the effect of weight reduction in overweight and obese men on their reproductive function.
Study Type
OBSERVATIONAL
Enrollment
300
self-directed weight loss, guided weight loss, weight loss by gastric by-pass surgery
Oslo University College
Oslo, Norway
RECRUITINGweight, height, % body fat, sperm (volume, concentration, motility, morphology, vitality), sperm DNA integrity, steroid hormones, gonadotropins, blood glucose, HbA1c, mCRP, lipids, adiponectins, fatty acid composition in serum and sperm phospholipids
Time frame: minimum three months
genetic variations in genes involved in metabolism and reproduction
Time frame: no time frame
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