AZD1305 Single and Multiple Ascending Dose Study in Healthy Japanese and Caucasian Subjects

Inclusion Criteria: * Healthy Japanese and Caucasian male subjects 20 to 45 years of age inclusive * Body weight between 50 and 85 kg, inclusive, with a Body Mass Index (BMI) ≥19 to ≤ 27 kg/m2 Exclusion Criteria: * Clinically significant illness, surgical procedure or trauma, within two weeks preceding the pre-entry visit until first administration of IP, as judged by the investigator * History of clinically significant gastrointestinal, mental, cardiac, renal or hepatic disorder, or other significant disease as judged by the investigator * Habitual smoker (daily use) of tobacco or daily use of nicotine-containing products