The primary objective for this study is to assess the safety and tolerability of AZD8329 when given as a single dose in increasing dose strength, and also to identify the highest tolerated dose for future studies.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
119
Research Site
Linköping, Sweden
Research Site
Uppsala, Sweden
Safety measurements (ECG's, Pulse, Blood Pressure, Safety Laboratory and Adverse Events)
Time frame: Safety will be monitored continously and safety assessments will be made on several occasions throughout the whole study.
PK samples for AZD8329
Time frame: Intense PK-sampling during the 24 hours following administration of investigational product and additional samples up to 72 hours after dose.
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