Airway complications are a significant cause of morbidity after lung transplantation (LTx). Bronchoscopic evaluation may help to identify risk factors for requiring interventions later.
The investigators evaluated lung transplant recipients prospectively. Adult patients surviving 90 day after LTx will be included. The investigators propose a classification of airway healing based on the endoscopic bronchial appearances at days 7, 14, 21, 90, 180 and 365 after LTx. A score system including mucosal healing, full tissue necrosis (=dehiscence), lose sutures, fibrin plugs, polyps and malacia will be developed (max. score 8 points/date). Endoscopic findings will be correlated with the development of obstructive airway complications (OAC, requiring \>1 intervention). Afterwards the new score system will be applied prospectively in the patients.
Study Type
OBSERVATIONAL
Enrollment
180
Hannover Medical School
Hanover, Germany
Primary endpoint of this study was any obstructive airway complication (AC) which required desobliterative intervention.
Time frame: 1 year
secondary endpoint included anastomosis-related death.
Time frame: 1 year
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