The primary aim of this study is to investigate the safety and tolerability of AZD2423 single doses in healthy volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
80
Research Site
Berlin, Germany
To assess the safety and tolerability of AZD2423 following administration of single ascending doses and if possible to estimate the maximum tolerated dose (MTD), if within the predefined exposure limits.
Time frame: 3 day residential period plus 7-10 days follow up
To characterise the pharmacokinetics of AZD2423 and provisionally assess the dose proportionality of the pharmacokinetics following administration of single ascending doses ofAZD2423.
Time frame: 3 day residential period plus 7-10 days follow up
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