Pilot Study of Duloxetine in Adult Attention Deficit Hyperactivity Disorder(ADHD)

Université de Montréal40 enrolled

Overview

The purpose of this study is to determine whether duloxetine is an effective treatment of attention deficit disorder in adults.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Attention Deficit Disorder With Hyperactivity

Interventions

duloxetineDRUG

60 mg capsule once per day for 6 weeks

placeboDRUG

one capsule of placebo taken one a day for 6 weeks

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of ADHD of at least moderate intensity * Able to give consent * Able to swallow capsules Exclusion Criteria: * Allergic or do not tolerate duloxetine * Under psychotherapy for ADHD * Taking a medication that interacts with duloxetine, including all psychotropic medication * Treated with medication for ADHD * Unstable medical condition * Severe renal insufficiency * Liver insufficiency * Substance/alcool abuse or dependency in the last 6 months * Pregnancy, nursing or inadequate contraceptive methods * Suicide or homicide risk * Organic brain syndrome * Any diagnosis of lifetime bipolar disorder or psychotic disorder, and any actual diagnosis of anxious disorder or major depressive disorder

Locations (1)

Centre Hospitalier Universitaire de Montréal: Hôpital Notre-Dame

Montreal, Quebec, Canada

Outcomes

Primary Outcomes

Impact of duloxetine on the Conners' Adult attention-Deficit/Hyperactivity Disorder Rating Scale-Observer Report:Screening Version (CAARS-O:SV) in adult ADHD subjects.