Effect of DMMET-01 on Insulin Sensitivity in Naive Type 2 Diabetes Patients (CLAMP)

Inclusion Criteria: * Ages eligible for study: 40 to 60 years * With type 2 diabetes evolution \< 5 years without pharmacological treatment 1 month prior to the screening * Fasting glucose = 130-200 mg/dL * AIc of 7% to 9% * Blood pressure \< 140/80 mmHg * Ability to communicate and meet the requirements of the study * Signed Written Informed Consent before to conducting any study * Body mass index (BMI) of 25 kg/m2 to 35 Kg/m2 Exclusion Criteria: * Suspected or confirmed pregnancy * Nursing * Inability to secure the non-pregnant during the study duration * Hypersensitivity to any biguanides * Use of an investigational drug within 30 days prior to the screening * Liver failure, heart failure, kidney failure or thyroid disease * Periods of acute or chronic diarrhea or vomiting * Chronic hepatic disease * Total Cholesterol \> 300 mg/dL * Triglycerides \> 400 mg/dL