Simplification From Protease Inhibitors to Raltegravir

Inclusion Criteria: * HIV1 sero-positive using standard diagnostic criteria * Plasma viral HIV-RNA below 50 copies/ml within 180 days prior to randomization * On therapy with protease inhibitors both ritonavir-boosted or un-boosted for at least 6 months prior to study entry Exclusion Criteria: * Pregnancy or breast feeding * Prior use of Integrase inhibitors * Alcohol or substance abuse if according to the investigator opinion would interfere with compliance * UIse of investigational medications within 30 days before study entry or during the trial