Brain imaging tests are routinely used to detect the presence of a brain tumor or to evaluate the response to treatment. Sometimes the images obtained are not specific and the only way to establish a diagnosis is by obtaining a tissue sample. The hypotheses of the study is to determine if multimodal MR technique will provide tissue signatures that differentiate between tumor progression and treatment related necrosis in high grade glioma patients.
Study Type
OBSERVATIONAL
Enrollment
12
The introduction of the 3T scanners provides a potential opportunity to improve the quality of imaging in neuro-oncology.
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
To prospectively acquire multiparameter MR variables at 1.5T and 3T MRI from treated high grade glioma patients to assign tissue signatures for tumor recurrence and radiation necrosis as established by pathologic examination.
Time frame: 24 months
To compare the predictive values of the multiparameter MR tissue signatures acquired at 1.5T and 3T
Time frame: 24 months
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