Role of Oxidized Regenerated Cellulose (ORC) Applied to "Dirty" Surgical Wounds

Catholic University of the Sacred Heart98 enrolled

Overview

The purpose of this study is to determine whether oxidized regenerated cellulose (ORC) is effective to reduce the risk of surgical site infections (SSI).

Surgical site infections (SSI) have significant clinical and economic repercussions since they still are the most common cause of nosocomial infections in surgical patients. It is important to bear in mind the growing number of SSI due to antibiotic-resistant microorganisms.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Infections

Interventions

oxidized regenerated cellulose (Fibrillar SURGICEL)DEVICE

one gauze made of ORC

iodoform gauzeDEVICE

one iodoform gauze

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * have an ileostomy or a colostomy * are candidates for an elective surgical procedure of ostomy closure Exclusion Criteria: * immunodeficiency * chronic use of corticosteroids or antibiotics * chemotherapy and/or radiotherapy in the last 30 days before closure of the stoma * concomitant foci of infection

Locations (1)

Digestive Surgery of the Catholic University of Sacred Heart

Rome, Italy

Outcomes

Primary Outcomes

to reduce the microbial load and, consequently, the infection rate as compared to conventional local wound treatment

Time frame: third post-operative day

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.