The aim of the randomized double blind trial with 134 patients presenting old world cutaneous leishmaniasis is: * to evaluate the clinical efficacy of electro-thermo-cauterisation (ETC) followed by moist wound treatment versus ETC followed by moist wound treatment plus 0.05 % pharmaceutical chlorite that has been used in three European countries (Germany, Austria and Switzerland) in wound care management for more than 20 years; * to judge whether early wound care management would present a viable improvement to the actual anti-parasitic treatments mostly neglecting the chronic wound problem and to evaluate its long-term effect on immunity through relapse control 6 months after wound healing.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
134
moist wound treatment plus 0.05 % pharmaceutical chlorite
physiological saline
German Medical Service
Kabul, Kabul, Afghanistan
Days for wound closure
Days for primary wound closure
Time frame: From the day of treatment start to the day of "wound closure"
Leishmania parasites load per gram of tissue before and after treatment
Parasite load per gram of tissue
Time frame: Before treatment start and at day "wound closure"
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