Study of Povidone Iodine to Reduce Pulmonary Infection in Head Trauma and Cerebral Hemorrhage in Intensive Care Unit

Inclusion Criteria: * Adults \> 18 years * Closed head trauma with a Glasgow Coma Score \<=8 or cerebral Hemorrhage with a Glasgow Coma Score of \<=8 * Expected need mechanical ventilation for \>=2 days * Written informed consent from the patient's next-of-kin. If no relative is present at the time of inclusion, the patients will be included according to the emergency procedure Exclusion Criteria: * Impossibility to perform oropharyngeal decontamination within 12 h following the initial episode * Facial injury with impossibility to perform the oropharyngeal decontamination * Tetraplegia * Known history of reaction to iodine * Respiratory disease or pulmonary infiltrate(s) at inclusion * Need for curative antibiotics * Mercurial antiseptics treatment * Pregnancy