ICU Cell Saver to Reduce Blood Transfusions in Cardiac

Cardiochirurgia E.H.350 enrolled

Overview

PURPOSE: Autotransfusion devices may be employed in cardiac surgery to decrease allogenic blood requirements. Limitations of previous trials include the use of cell saver systems in selected high risk patients only or the lack of blood transfusion-sparing strategies. The aim of this prospective randomized study is to evaluate the efficacy of cell salvage CardioPAT routinely used in cardiac surgery. METHODS: The investigators will randomize 350 patients in two groups: group 1 receives a CardioPAT cell saver device (175 patients), group 2 doesn't receive any cell saver device. The incidence of allogenic blood transfusion and clinical outcome in both groups are evaluated.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

350

Conditions

Blood Transfusion Cardiac Surgery

Interventions

Cell Saver System at bedside for ICU stay

Traditional Chest DrainsDEVICE

Chest drains as usual with no possibility to reinfuse lost blood

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * All patients presenting for cardiac Surgery Exclusion Criteria: * None

Locations (1)

Cardiochirurgia European Hospital

Rome, Italy

Outcomes

Primary Outcomes

Number of Transfusions per patient

Time frame: 10 days after surgery

Secondary Outcomes

Mortality

Time frame: 30 days after surgery

Data from ClinicalTrials.gov

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