Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome

University of Leipzig267 enrolled

Overview

In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury. This allows for quantifying the extent of salvaged myocardium after reperfusion as a potential strong end point for clinical trials and outcome. The aim of the present study is to determine the prognostic significance and determinants of myocardial salvage assessed by CMR in reperfused ST-elevation myocardial infarction (STEMI).

Study Type

OBSERVATIONAL

Enrollment

267

Conditions

ST-Elevation Myocardial Infarction

Interventions

magnetic resonance imagingOTHER

magnetic resonance imaging is used for prognosis assessment

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ST-elevation myocardial infarction \< 12 hours * primary percutaneous coronary intervention Exclusion Criteria: * previous myocardial infarction * prior fibrinolysis * contraindications to CMR at study entry (such as implanted pacemakers, defibrillators, claustrophobia or metallic intracranial implants)

Locations (1)

University of Leipzig - Heart Center

Leipzig, Germany

Outcomes

Primary Outcomes

Major adverse cardiac events

Time frame: 6 months

Secondary Outcomes

Mortality

Time frame: 6 months

Data from ClinicalTrials.gov

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