Miralax (PEG 3350) has been shown to be a safe and uncomplicated bowel preparation prior to colonoscopy in pediatric populations. This study seeks to confirm the efficacy of this bowel cleansing regimen in adults and to determine the benefit of adding a pretreatment medication to this bowel preparation. The tolerability of Miralax will hopefully improve patient satisfaction with colonoscopy and decrease their reluctance to be screened because of the uncomfortable taste and side effects of bowel preparation regimens.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
425
Miralax 255gm bottle
Amitiza 24mcg gelcap
Bisacodyl 5mg tab x2
Golytely 1 gallon
Brooke Army Medical Center
San Antonio, Texas, United States
The Cleanliness of the Prep as Measured by the Ottawa Scale
Bowel cleansing was evaluated with the Ottawa bowel preparation scale by each endoscopist during the endoscopy. Neither the endoscopist nor the endoscopy nurse was aware of the bowel preparation used prior to the colonoscopy. The Ottawa bowel preparation scale is a validated tool and was used in this study to provide a reliable quality assessment of the bowel preparation used for colonoscopy. This validated scale rates each section of the colon, the right, the mid, and the rectosigmoid colon, on a 5-point scale (0-4), as well as a global 3-point rating for overall colonic fluid (0-2). The total score ranges from 0 to 14. An excellent preparation with little fluid would score 0-3, a good preparation 4-6, while scores higher than 7 would indicate progressively worsening bowel preparations. A completely unprepared colon would score 11-14, depending on the amount of colonic fluid.
Time frame: measured at the time of colonoscopy
Patient Satisfaction With the Prep Measured by 5 Point Likert Scale
patient satisfaction based on a Likert Scale from 0-5 (5 being completely satisfied and 0 being not satisfied)
Time frame: measured at check in to colonoscopy
Procedure Time
total colonoscopy procedure time
Time frame: measured at the time of colonoscopy
Polyps Detected
Number of polyps
Time frame: measured at the time of colonoscopy
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